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Abstract #0006

Cerebral Myelin Content Correlation with Mathematical Abilities in Young Children

Richard Davis Holmes1, Silvia Mazabel2, Burkhard Maedler3, Christian Denk, Linda Siegel4, Christian Beaulieu5, Alex MacKay6

1UBC MRI Research Centre, University of British Columbia, Vancouver, British Columbia, Canada; 2Department of Educational and Counselling Psychology, and Special Education, University of British Columbia; 3Philips Medical Systems; 4Department of Educational and Counselling Psychology and Special Education, University of British Columbia; 5Department of Biomedical Engineering, University of Alberta; 6Department of Physics and Astronomy, University of British Columbia

Structural imaging applied to children with wide ranging mathematical abilities has the potential to elucidate the question of what neural circuits underly computation based tasks. The present investigation analyzed the myelin water fraction images of 20 children in a standard space to deduce correlations between myelin content and math abilities. Subjects wrote a calculation-based test and an applied problem-based test. The results implicated occipital/parietal white matter, the right anterior limb of the internal capsule and the left external capsule with positive correlations of 0.61,0.65 and 0.60, respectively.