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Abstract #0014

Optimization of Susceptibility Weighted Imaging at 7T for Improved Detection of Alzheimers Amyloid Plaques Associated with Iron in Human Postmortem Brain

Yulin Ge1, Tang Lin1, Daniel K. Sodickson1, Edward Lin1, Jing Yang1, E Mark Haacke2, Mony de Leon1, Robert I. Grossman1, Thomas Wisniewski1

1New York University School of Medicine, New York City, NY, United States; 2Wayne State University, Detroit, MI

Due to markedly enhanced susceptibility contrast and signal-to-noise ratio at ultra-high-field MR, it is possible to detect amyloid plaques associated with iron deposition using susceptibility weighted imaging in patients with AD.