Abstract #0025

Spatial Localization Accomplished by Sensitivity Heterogeneity

Li An¹, Steven Warach¹, Jun Shen²

¹National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States; ²National Institute of Mental Health, National Institutes of Health, Bethesda, MD, United States

This work demonstrates a new method that allows multi-compartmental spatial localization based on the heterogeneity of sensitivity profiles of phased array receiver coils. This method offers an alternative to SENSE-CSI for performing spectroscopy using phased array coils. It allows the user to manually prescribe compartments following natural anatomical or physiological boundaries to reduce partial volume artifacts associated with conventional CSI and SENSE-CSI. In vivo application using PRESS and an eight-element phased array head coil demonstrates that this method can extract spectra from stroke tissue and normal tissue in 4 seconds.