Bastiaan Versluis1, Marjolein HG Dremmen1, Patty J. Nelemans2, Joachim E. Wildberger1, Tim Leiner1, Walter H. Backes1
Objective characterization of peripheral arterial disease (PAD) severity remains difficult purely on the basis of morphological assessement. We describe a method to determine rest flow and blood flow reserve capacity (BFRC) of the popliteal artery, using serial velocity encoded 2D MR cine PCA flow measurements. Using this method, we found a strong reduction in rest flow, maximum flow and BFRC in 10 patients with intermittent claudication compared to 10 healthy subjects. This method can potentially be used to supplement MR angiography to objectively characterize PAD disease severity and to monitor therapy efficacy in intermittent claudication.