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Abstract #0083

Validation of Functional Diffusion Maps (FDMs) as a Biomarker for Human Glioma Cellularity

Benjamin M. Ellingson1,2, Mark G. Malkin2,3, Scott D. Rand1,2, Jennifer M. Connelly2,3, Carolyn Quincey3, Pete S. LaViolette2,4, Devyani P. Bedakar1,2, Kathleen M. Schmainda1,2

1Dept. of Radiology, Medical College of Wisconsin, Milwaukee, WI, United States; 2Translational Brain Tumor Program, Medical College of Wisconsin, Milwaukee, WI, United States; 3Dept. of Neurology and Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States; 4Dept. of Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States


The purpose of the current study was to comprehensively validate the assumptions made in human functional diffusion map (fDM) analyses and provide a biological and clinical basis for thresholds used in fDM tissue classification.

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