Jing Gu1, Yok-Lam Kwong2, Tao Chan1, Wing-Yan Au2, Queenie Chan3, JingBo Zhang1,4, Raymond Liang2, Pek-Lan Khong1
1Diagnostic Radiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China; 2Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China; 3Philips Healthcare, Philips Electronics Hong Kong Limited, Hong Kong; 4Memorial Sloan-Kettering Cancer Center, United States
The aim of this study was to evaluate the diagnostic performance of DWIBS in detection of lymphoma compared with PET/CT, and to assess the correlation between ADC and SUV in lymphoma lesions. We found that (1) DWIBS provides satisfactory diagnostic accuracy in lymphoma compared with PET/CT, and with the advantage of no ionizing radiation. (2) There were significant differences in ADCmin and SUVmax between aggressive and indolent B-cell lymphoma. ADCmin may therefore be another useful quantitative marker for tumor characterization and classification. (3) Negative correlation was found between ADCmin and SUVmax suggesting an association between tumor cellularity and metabolic activity.