Yurui Gao1, Ann S. Choe2, Xia Li3,
Iwona Stepniewska4, Adam Anderson
1BME, VUIIS, Nashville, TN, United
States; 2BME, VUIIS, United States; 3EECS, VUIIS,
United States; 4Psychological Sciences at Vanderbilt, United
States
Since
DTI tractography is used to examine the neural connectivity between
specialized cortical regions of the brain, it is important to evaluate the
agreement between the connectivity derived from DTI tractography and
corresponding histological information. We reconstruct the projection regions
connecting to the primary motor cortex (M1) of the squirrel monkey, based on
histological segmentation and compare these regions with the locations of the
terminals of DTI fibers penetrating the same M1 region. Quantitative
comparison shows an approximate agreement but also limits of applying DTI
tractography to predict M1 connectivity.
Keywords