Abstract #0123

Exploring the Reproducibility and Consistency of Diffusion-Weighted Functional Magnetic Resonance Imaging During Visual Stimulation Using Population-Based Activation Map

Ruiwang Huang¹, Bida Zhang²

¹State Key Lab of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing , 100875, China; ²Siemens Mindit Magnetic Resonance, Siemens Healthcare MR Collaboration NE Asia,

Human brain functional studies have been generally performed with BOLD-fMRI, but the spatial location and distribution of the activation map is not accurate. Recently, it has been suggested that the diffusion-weighted functional magnetic resonance imaging (dFMRI) may be sensitive to the true neuronal activation. However, the influence of b-value on the activation region is not fully understood. Here we performed a visual stimulation study on twelve subjects with dFMRI (b-value=50/400/800/1200/1600s/mm2) and BOLD-fMRI, and constructed the population-based activation maps. The locations and distributions of dFMRI and BOLD-fMRI measurements were compared, and the consistency of dFMRI study was evaluated.