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Abstract #0147

Transient RF Spoiling for 3D Look-Locker Acquisitions

Trevor Wade1,2, Charles McKenzie1,3, Brian Rutt4

1Imaging Research Laboratories, Robarts Research Institute, London, ON, Canada; 2Biomedical Engineering, The University of Western Ontario, London, ON, Canada; 3Medical Biophysics, The University of Western Ontario, London, ON, Canada; 4Diagnostic Radiology and Richard M Lucas Center for Imaging, Stanford University, Stanford, CA, United States

Theoretical and experimental investigation of RF spoiling in the special case of accelerated 3D Look-Locker imaging has led to an improved value for the phase increment used in the standard RF spoiling scheme. Poor choice of phase increment leads to an inversion recovery curve that deviates significantly from the theoretical ideal, leading to an inaccurate estimate of the recovery time constant. Simulations were used to determine improved values for the phase increment based on minimizing summed squared differences, or time constant measurement accuracy. These were tested experimentally and found to be superior to previously reported values for most imaging parameters.