Sascha Krueger1, Ronald Holthuizen2, Jouke Smink2, Steffen Weiss1, Oliver Lips1, Bernd David1, Daniel Wirtz1, Steen Fjord Pedersen3, Dennis Caulfield4, Julian Bostock4, Gang Gao4, Phani Chinchapatnam4, Tobias Schaeffter4, Reza Razavi4
1Philips Research Europe, Hamburg, Germany; 2Philips Healthcare, Best, Netherlands; 3MR Research Centre, Skejby Hospital, Aarhus, Denmark; 4Division of Imaging Sciences, King's College, London, United Kingdom
Cardiac arrhythmias, e.g. atrial fibrillation and ventricular tachycardia, are increasingly treated by electrophysiological (EP) interventions. Applying MR for guiding these interventions offers advantages like 3D visualization of the cardiac soft tissue in relation to the catheter, visualization of the treatment effect and absence of ionizing radiation. Making the step towards clinical MR-guided EP interventions requires a focus on RF safety of the devices, localization accuracy of the catheters, guidance of the procedure, intra-cardiac signal quality and procedure workflow. Here, an MR-EP suite based on an MR-EP Navigator application with a real-time interface to the MR system and therapy equipment is demonstrated along with specialized MR-EP catheters. These catheters are based on RF-safe concepts for both, MR- and EP functionality. RF-safety, localization accuracy and EP signal quality of these devices, and the operation of the MR-EP suite and the workflow of the MR-EP Navigator are demonstrated in a series of pre-clinical MR-guided EP experiments.