Joanne Rachel Hale1, Matthew Brookes1,
Claire Stevenson1, Johanna Zumer1, Gareth Barnes2,
Julia Owen3, Susan Francis1, Srikantan Nagarajan3,
Peter Morris1
1SPMMRC, University of Nottingham,
Nottingham, Nottinghamshire, United Kingdom; 2University College
London, London, United Kingdom; 3University of California, San
Francisco, San Francisco, CA, United States
Recently,
interest has increased in studying resting state fluctuations in BOLD fMRI
and work has shown correlation between BOLD signals from spatially separate
but functionally related brain regions. Unfortunately, fMRI signals are
affected by non-neuronal physiological artifacts which can lead to spurious
connectivity measurements. The ability to investigate the neuronal activity
underlying BOLD connectivity is therefore important. Here we use MEG and 7T
fMRI to measure independently resting state sensorimotor cortex connectivity.
We show that beta-band fluctuations are implicated in sensorimotor network
connectivity, adding weight to previous EEG/fMRI results implying a neural
oscillatory basis to resting state BOLD signals.
Keywords