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Abstract #0377

High Resolution 31P Magnetic Resonance Spectroscopic Imaging of the Human Brain at 7T.

Jannie Petra Wijnen1, Arend Heerschap1, Tom W.J. Scheenen1,2

1Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, Gelderland, Netherlands; 2Erwin L. Hahn Institute for Magnetic Resonance Imaging, Essen, Germany

We demonstrated the use of a surface 31P quadrature coil in combination with a 1H CP head coil for 31P MRSI of the brain at 7T with high sensitivity and spatial resolution. 31P MRS was run with a pulse acquire MRSI sequence with adiabatic excitation. With this method we detected phosphorylated signals from the energy metabolism in the brain as well as resonances from phosphomono and diester compounds and inorganic phosphate in the human brain within relatively short acquisition times (16 or 25minutes).