Jake Samuel Burrell1, Jane Halliday2,
Simon Walker-Samuel3, John C. Waterton2, Philip J.
Withers4, Robert S. Bradley4, Jessica Boult1,
Yann Jamin1, Lauren C. Baker1, Simon P. Robinson1
1The Institute of Cancer Research,
Sutton, Surrey, United Kingdom; 2AstraZeneca, Manchester, United
Kingdom; 3UCL, London, United Kingdom; 4School of
Materials, University of Manchester, Manchester, United Kingdom
Susceptibility
contrast MRI vessel size index (VSI) derived vessel diameters were compared
with vessel diameters measured from vascular corrosion casts of the same
SW1222 colorectal tumours. Good agreement was found between the MRI and
vascular corrosion cast derived vessel sizes, reported as 38 6m and 39
2m respectively. This work helps to qualify non-invasive MRI vessel size
measurements with appropriate histology.