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Abstract #0518

Whole Brain Pseudo Continuous ASL at 7T Using a Single Coil for Imaging and Labeling.

Wouter M. Teeuwisse1, Andrew Webb1, Matthias J.P. van Osch1

1C.J.Gorter Center, Radiology, Leiden University Medical Center, Leiden, Netherlands

In this study, whole brain pseudo continuous ASL (pCASL) is implemented at 7T, using the same RF coil for labeling and imaging. The magnitude of B0 inhomogeneities, RF penetration and f0-offsets were measured. For optimal labeling, B0 changes along the vessels were compensated by adjusting the average labeling gradient. A subject-specific frequency offset for the label pulses was calculated and implemented as was the incorporation of high dielectric material placed around the head and neck for higher B1 delivery in the neck. After implementing all of these improvements whole brain pCASL was successfully performed at 7T.