Robust Prescan for Pseudo-Continuous Arterial Spin Labeling at 7T: Estimation and Correction for Off-Resonance Effects

Wen-Ming Luh¹, S Lalith Talagala², Peter A. Bandettini¹

Pseudo-continuous arterial spin labeling can provide optimal SNR efficiency with sufficient long tag at high fields such as 7T but is very sensitive to off-resonance fields at tagging location as often observed at 7T. Here we demonstrate a robust approach using pair-wise modulation of tagging frequency offset with high SNR images from large voxels and short post labeling delay to derive a necessary prescan procedure for estimating and correcting off-resonance effects in 1 minute.