Abstract #0529

Preliminary Human Evaluation of MRI-Guided Transurethral Ultrasound Therapy for the Treatment of Localized Prostate Cancer

Rajiv Chopra^1,2, Michael Bronskill^1,2, Masoom Haider^3,4, Laurence Klotz^5,6

¹Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; ²Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; ³Medical Imaging, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; ⁴Medical Imaging, University of Toronto, Toronto, Ontario, Canada; ⁵Urology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; ⁶Surgery, University of Toronto, Toronto, Ontario, Canada

MRI-guided transurethral ultrasound therapy is a minimally-invasive treatment for localized prostate cancer. The purpose of this study was to evaluate the feasibility of performing this treatment in humans. An initial clinical evaluation in prostate cancer patients destined for radical prostatectomy was performed. The predicted thermal damage zone was compared with the actual tissue damage measured on histology.