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Abstract #0575

Apparent Fibre Density: A New Measure for High Angular Resolution Diffusion-Weighted Image Analysis

David Raffelt1,2, Stuart Crozier2, Alan Connelly3,4, Olivier Salvado1, J-Donald Tournier3,4

1The Australian E-Health Research Centre, CSIRO, Brisbane, QLD, Australia; 2Department of Biomedical Engineering, University of Queensland, Brisbane, QLD, Australia; 3Brain Research Institute, Florey Neuroscience Institutes (Austin), Melbourne, VIC, Australia; 4Department of Medicine, University of Melbourne, Melbourne, VIC, Australia

Apparent Fibre Density is a new measure that is based on information provided by Fibre Orientation Distributions. Voxel wise comparisons of Apparent Fibre Density can be made over all orientations permitting differences to be attributed to a single fibre within voxels with multiple fibre populations.