Abstract #0575

Apparent Fibre Density: A New Measure for High Angular Resolution Diffusion-Weighted Image Analysis

David Raffelt^1,2, Stuart Crozier², Alan Connelly^3,4, Olivier Salvado¹, J-Donald Tournier^3,4

¹The Australian E-Health Research Centre, CSIRO, Brisbane, QLD, Australia; ²Department of Biomedical Engineering, University of Queensland, Brisbane, QLD, Australia; ³Brain Research Institute, Florey Neuroscience Institutes (Austin), Melbourne, VIC, Australia; ⁴Department of Medicine, University of Melbourne, Melbourne, VIC, Australia

Apparent Fibre Density is a new measure that is based on information provided by Fibre Orientation Distributions. Voxel wise comparisons of Apparent Fibre Density can be made over all orientations permitting differences to be attributed to a single fibre within voxels with multiple fibre populations.