Abstract #0636

Effect of Off-Frequency Encoding in Magnetic Resonance Elastography

Curtis L. Johnson¹, Danchin Chen¹, Harish Sharma², Bradley P. Sutton,^2,3, William C. Olivero,^2,4, John G. Georgiadis^1,2

¹Mechanical Science and Engineering Department, University of Illinois at Urbana-Champaign, Urbana, IL, United States; ²Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, United States; ³Bioengineering Department, University of Illinois at Urbana-Champaign, Urbana, IL, United States; ⁴Department of Neurosurgery, University of Illinois at Urbana-Champaign, Urbana, IL, United States

The effects of encoding displacement at a frequency other than the driving frequency with Magnetic Resonance Elastography (MRE) were investigated. Off-frequency responses can occur due to possible nonlinearities in the overall dynamic system being actuated. Results demonstrated that undesired off-frequency encoding could result in errors in mean estimated stiffness of tissue, as well as local fluctuations in estimated stiffness, which will have implications for MRE with nonlinear dynamic systems.