Abstract #0733

Assessment of Melanoma Extent and Melanoma Metastases Invasion Using Electron Paramagnetic Resonance and Bioluminescence Imaging

Quentin Godechal¹, Florence Defresne², Philippe Leveque¹, Jean-Franois Baurain³, Olivier Feron², Bernard Gallez¹

¹Biomedical Magnetic Resonance Unit, Universit Catholique de Louvain, Bruxelles, Belgium; ²Pharmacotherapy Unit, Universit Catholique de Louvain, Bruxelles, Belgium; ³Medical Oncology Unit, Universit Catholique de Louvain, Bruxelles, Belgium

Malignant melanoma is a skin tumor characterized by the uncontrolled proliferation of melanocytes, which can lead to metastasis mainly in lungs. The incidence of melanoma is rising each year. For this reason, it is essential to develop new effective methods able to detect melanoma. The purpose of the present study is to assess the ability of EPR to detect and measure the colonization of lungs by melanoma metastases. Results will be compared to results obtained with bioluminescence imaging in order to validate the EPR method.