Jue Wu1, Suyash P. Awate2, Daniel Licht3, Catherine Limperopoulos4, James C. Gee1
1Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2Siemens Corporate Research, Princeton, NJ, United States; 3Children's Hospital of Philadelphia, Philadelphia, PA, United States; 4Mcgill University, Montreal, Quebec, Canada
Eight cortical folding measures were applied to T2w in vivo MRIs of 40 normal fetuses with varied gestational ages. Correlations of these measures with gestational age are reported and Gaussian curvature L2 norm and intrinsic curvature index are the two most correlated measures. These measures may be help in characterization of normal neurodevelopment and in detection of abnormal brain growth in fetuses.