Jue Wu1, Suyash P. Awate2, Daniel
Licht3, Catherine Limperopoulos4, James C. Gee1
1Department of Radiology, University of
Pennsylvania, Philadelphia, PA, United States; 2Siemens Corporate
Research, Princeton, NJ, United States; 3Children's Hospital of
Philadelphia, Philadelphia, PA, United States; 4Mcgill University,
Montreal, Quebec, Canada
Eight
cortical folding measures were applied to T2w in vivo MRIs of 40 normal
fetuses with varied gestational ages. Correlations of these measures with
gestational age are reported and Gaussian curvature L2 norm and intrinsic
curvature index are the two most correlated measures. These measures may be
help in characterization of normal neurodevelopment and in detection of
abnormal brain growth in fetuses.