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Abstract #0743

The Functional-Structural Interplay During First Two Years' Brain Development

Wei Gao1, Pew-Thian Yap2, Hongtu Zhu3, Kelly Giovanello4, Keith Smith2, John Gilmore5, Weili Lin6

1Biomedical Engineering, UNC-Chapel Hill, Chapel Hill, NC, United States; 2Radiology, University of North Carolina-Chapel Hill, Chapel Hill, NC, United States; 3Biostatistics and Biomedical Research Imaging Center, University of North Carolina-Chapel Hill, Chapel Hill, NC, United States; 4Psychology and Biomedical Research Imaging Center, University of North Carolina-Chapel Hill, Chapel Hill, NC, United States; 5Psychiatry, University of North Carolina-Chapel Hill, Chapel Hill, NC, United States; 6Radiology and Biomedical Research Imaging Center, University of North Carolina-Chapel Hill, Chapel Hill, NC, United States


In this study, normal and healthy pediatric subjects aged between 2wk to 2 yrs were studied so as to directly compare the temporal evolution of brain functional and structural connectivity. In so doing, we aim to determine the temporal correlation between functional and structural connectivity during the first two years of life and to reveal whether or not maturation of structural connectivity is needed for functional connectivity.

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