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Abstract #0759

Fourier Analysis of STimulated Echoes (FAST) for Quantitative Analysis of Left Ventricular Torsion

Meral Reyhan1, Daniel B. Ennis1, Yutaka Natsuaki2

1Radiological Sciences, University of California, Los Angeles, CA, United States; 2Siemens Medical Solutions USA, Inc., Los Angeles, CA, United States

Left ventricular (LV) torsion is an important measure of LV performance. This study validates a novel quantitative method (Fourier Analysis of STimulated echoes - FAST) for the rapid quantification of LV torsion by comparison to a gold standard method (FindTags) and finds no statistical difference between the methods in six canine studies. The intraobserver coefficient of variation (CV) for each observer was 4.2% and 2.3%. The interobserver CV was 8.4% and 5.4%. FAST analysis of LV torsion in six healthy-subjects demonstrates quantitation of systolic torsion and early untwisting. FAST is a highly reproducible and rapid (<3 minutes-per-study) quantitative method.