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Abstract #0805

Improved Fat-Suppression for Unspoiled GRASS Imaging of the Knee Using Multi-Peak IDEAL Chemical Shift Fat-Water Separation

Richard Kijowski1, Catherine Debra Hines2, Huanzhou Yu3, Scott Brian Reeder1,2

1Radiology, University of Wisconsin, Madison, WI, United States; 2Medical Physics, University of Wisconsin, Madison, WI, United States; 3GE Healthcare, Applied Science Laboratory, Menlo Park, CA, United States

This study was performed to demonstrate improvements in the quality of fat-suppression for unspoiled GRASS imaging of the knee using multi-peak fat spectral modeling and IDEAL fat-water separation. An IDEAL-GRASS sequence was performed at 3.0T on the knees of 10 asymptomatic volunteers. The IDEAL-GRASS images were reconstructed using a single-peak method and a multi-peak method that more accurately models the NMR spectrum of fat. Multi-peak IDEAL-GRASS had significantly greater (p<0.001) suppression of bone marrow signal and significantly higher (p<0.001) CNR between cartilage and bone marrow than single-peak IDEAL-GRASS.