Meeting Banner
Abstract #0815

dGEMRIC Evaluation 9 to 20 Years After Autologous Chondrocyte Implantation in the Knee

Barbro Danielson1, Haris Vasiliadis2, Maria Ljungberg3, Sowmya Vijayakumar4, Nitya Krishnan4, Deborah Burstein4, Lars Peterson5, Brian McKeon6

1Musculoskeletal Section, Department of Radiology, Sahlgrenska University Hospital, Gothenburg, Sweden; 2Molecular Cell Biology and Regenerative Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden; 3Radiation Physics, University of Gothenburg, Gothenburg, Sweden; 4Department of Radiology, Beth Israel Deaconess Medical Center, Boston, MA, United States; 5Orthopedics, Sahlgrenska University Hospital, Sweden; 6New England Baptist Hospital, Boston, United States

The study assessed the long-term status of isolated cartilage lesions in the knee after ACT using dGEMRIC. Scans were obtained from 31 patients (5 bilateral lesions) total of 36 lesion sites, representing an f/u period of 9.5 to18.5 years post-implant. The dGEMRIC Index of the implant was greater than 90% of the value of the dGEMRIC Index for surrounding native tissue in 70% of cases, even more than 10 years after the implantation.