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Abstract #0931

Implementation and Validation of Localized Constant-Time PRESS on a 7T MRI/MRS Scanner

Bhaskaran David Prakash1, Loyola D'Silva1, Kishore Bhakoo1, David Townsend1, S. Sendhil Velan1

1Laboratory of Molecular Imaging, Singapore Bioimaging Consortium, Singapore, Singapore

We have implemented and validated the LCT-PRESS technique in healthy rat brain. This sequence clearly demonstrates superior resolution and permits reliable detection of several brain metabolites that overlap in conventional techniques. The LCT-PRESS sequence performs this separation due to its incorporation of constant-time evolution, resulting in spin-spin decoupling along the F1 dimension.