A New Detection Scheme for Ultrafast 2D COSY

Shuhui Cai¹, Mingfang Zhao¹, Zhong Chen¹

Two-dimensional NMR techniques greatly extend the application fields of NMR spectroscopy. Unfortunately, the collection of numerous t₁ increments leads 2D experiments fairly time-consuming. The spatial encoding ultrafast technique enables fast acquisition of 2D NMR spectra. In this abstract, a new ultrafast 2D COSY method based on continuous constant-time phase-modulated spatial encoding was proposed. Compared to the previous real-time phase-modulated method, the present method not only gives much better spectral signal-to-noise ratio and resolution, but also is much easier to implement.