Elena
Vescovo1, Federico Di Cesare2, Dan Stefan2,
Danielle Graveron-Demilly2, Steve Williams3
1Image Science and Biomedical
Engineering,, The University of Manchester, Manchester, Greater Manchester,
United Kingdom; 2Laboratoire CREATIS-LRMN, CNRS UMR 5220,
Universite' Claude Bernard Lyon 1, Lyon, France; 3Image Science and
Biomedical Engineering, The University of Manchester, Manchester, Greater
Manchester, United Kingdom
Magnetic
resonance spectroscopy can provide a non-invasive approach to measure the
internal temperature of the brain; it relies on the linear relationship
between the 1H MR resonance frequency of
water in the tissue and the tissues temperature. The absolute
temperature is obtained by measuring the chemical shift of water relative to
a reference compound such as N-Acetylaspartate (NAA). To convert the frequency
difference between these two signals into temperature, it is necessary to
apply a calibration curve. All these procedures could be performed using a
plugin of jMRUI, a Java-based Graphical User Interface that allows
time-domains analysis of MRS, MRSI and HRMS-NMR signals. In this work we used
jMRUI v4.x, a new version of the software that enabled the user to add their
own plugin.