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Abstract #1083

Isotropic Sub-Millimeter FMRI in Humans at 7T

Robin Martin Heidemann1, Dimo Ivanov1, Robert Trampel1, Joeran Lepsien1, Fabrizio Fasano2, Josef Pfeuffer3, Robert Turner1

1Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; 2Fondazione Santa Lucia, Rome, Italy; 3Siemens Healthcare Sector, Erlangen, Germany

For isotropic high resolution fMRI at ultra-high field strength, susceptibility effects and T2* decay must be properly addressed. A combination of reduced FOV imaging (zoomed imaging) and parallel imaging is optimized here, achieving acceleration factors of up to 5.5. The high acceleration reduces distortions and image blurring, while incurring no other image artifacts. With this approach, high quality single-shot EPI acquisitions can be obtained with an isotropic resolution of 0.65 mm and sufficient coverage for e.g. fMRI in the visual cortex of the human brain.