The Orbitofrontal FMRI Experiment with Correction of the Susceptibility Artifact

Sung Suk Oh¹, SungDae Yun¹, Bumseok Jeong², HyunWook Park¹

The signal loss by the susceptibility artifact makes it difficult analyze the fMRI data of the orbitofrontal region of the brain. In addition, an EPI sequence, which is used in many fMRI experiments, has the geometric distortion and Nyqust ghosts. For the fMRI experiment with correction of these artifact and distortion, we used a flat RF pulse which provides nearly constant signal intensity against the magnetic susceptibility and a gradient echo sequence. In the result, it is shown that the signal loss in the orbitofrontal region of the brain is recovered without geometric distortion and Nyqust ghosts and the activation in that region was analyzed successfully.