Meeting Banner
Abstract #1116

Hemodynamic Response Function (HRF) Modulation by Inhaled CO2 Concentration Using Event-Related FMRI

Chao-Chun Lin1,2, Yi-Jui Liu3,4, Chien-Kuo Chen3, Hsiao-Wei Peng3, Kuo-Fang Shao4, Wu-Chung Shen1,5, Chang Hing-Chiu6

1Department of Radiology, China Medical University Hospital, Taichung, Taiwan, Taiwan; 2Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, Taiwan; 3Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan; 4Master's Program in Biomedical Informatics and Biomedical Engineering, Feng Chia University, Taichun, Taiwan; 5School of Medicine, China Medical University, Taichung, Taiwan; 6Applied Science Laboratory, GE Healthcare Taiwan, Taipei, Taiwan

The purpose of this study was to evaluate the hemodynamic response function (HRF) change after inhalation of different carbon dioxide concentrations. Using event-related method investigate the transient hemodynamic response function by short-time visual stimulus with different CO2 concentrations. Our results show that the peak of HRF curve is decreased and delayed with increased inhaled CO2 concentrations, and the width of HRF curve is wider with higher inhaled CO2 concentration.