Abstract #1176

The Dependency of Age-Related Change of Brain Activation on the Visual Stimuli - Demand-Reservation Balance

Toshiharu Nakai¹, Makoto Miyakoshi¹, Epifanio Bagarinao¹, Masaki Yoshida², Chikako Nakai³, Kayako Matsuo⁴

¹Functional Brain Imaging Lab, National Center for Geriatrics and Gerontology, Ohbu, Aichi, Japan; ²Ophthalmology, The Jikei University, Tokyo, Japan; ³School of Health Sciences, Toyoshashi Sozo University, Toyohashi, Aichi; ⁴Psychology, National Taiwan University, Taipei, Taiwan

We evaluated the effect task demand for visual processing on the age-related change of the brain activation in healthy subjects. In the elderly subjects, the % HRF in V1 was reduced by the flickering checkerboard stimuli. By a visuo-motor translation task the % HRF in BA19/7/39 was increased in the elderly, while no significant difference of % HRF was detected between the two age groups in V1. HRF analysis suggested that age-related change of % HRF may depend on the existence of neuronal network to compensate the potential functional decline according to aging.