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Abstract #1179

A FMRI Study of Temporary Hearing Threshold Shift

Piotr Bogorodzki1, Tomasz Wolak2, Krzysztof Kochanek2, Ewa Piatkowska-Janko1, Piotr Skarzynski2, Adam Pilka2, Jozef Kotus3, Andrzej Czyzewski3

1Institute of Radioelectronics, Warsaw University of Technology, Warsaw, Poland; 2Institute of Physiology and Pathology of Hearing; 3Gdansk University of Technology, Gdansk, Poland

Several empirical studies have shown, that long lasting acoustic noise exposure causes on humans effect called Temporary Hearing Threshold Shift (TTS). This work presents results from 15 healthy subjects participating in a fMRI study of TTS consisting of two runs: ⣣pre⣣ with silent GE EPI scanning and ⣣post⣣ identical to ⣣⣣pre⣣, but after 15min high volume noise exposure (causing a mean 12 dB TTS effect). Group level analysis showed activations in auditory cortex (T=13.3 in lh, and 10.45 in rh). A two-sample T-test fails for post>pre contrast, however detailed ROI analysis shows differences in sub-auditory areas.