Dissociation of BOLD and Local Field Potentials

Wen-Ju Pan¹, Matthew Magnuson¹, Garth Thompson¹, Waqas Majeed¹, Dieter Jaeger², Shella Keilholz¹

To examine what extent consistence of the measurements between BOLD fMRI and local field potential (LFP), we evaluated BOLD and LFP simultaneously in rat somatosensory cortex with a combined measurement technique. The preliminary results indicated a dissociation between BOLD and LFP during low-level neural activity, which might mirror the limitation of neurovascular coupling, the bridge between BOLD and neural activity.