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Abstract #1211

Dissociation of BOLD and Local Field Potentials

Wen-Ju Pan1, Matthew Magnuson1, Garth Thompson1, Waqas Majeed1, Dieter Jaeger2, Shella Keilholz1

1BME, Georgia Institute of Technology / Emory University, Atlanta, GA, United States; 2Biology, Emory University, Atlanta, GA, United States

To examine what extent consistence of the measurements between BOLD fMRI and local field potential (LFP), we evaluated BOLD and LFP simultaneously in rat somatosensory cortex with a combined measurement technique. The preliminary results indicated a dissociation between BOLD and LFP during low-level neural activity, which might mirror the limitation of neurovascular coupling, the bridge between BOLD and neural activity.