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Abstract #1232

Clinical 3.0T Magnetic Resonance Scanner Can Be Used for Imaging of Mouse Atherosclerotic LesionsĪ¦

Xubin Li1,2, Huidong Gu1, Hongqing Feng1, Xiangke Du2, Bensheng Qiu1, Xiaoming Yang1

1Image-Guided Bio-Molecular Intervention Researchers, Department of Radiology; Institute for Stem Cel, University of Washington School of Medicine, Seattle, WA, United States; 2Radiology, Peking University People's Hospital, Beijing, China

The aim of this study was to explore the possibility of generating high-resolution MR images of atherosclerotic aortic walls/plaques of mice using a clinical 3.0 Tesla MR scanner. This study demonstrates that clinical 3.0T MR scanners can be used for high-resolution imaging of atherosclerotic vascular walls and lesions in mice, which is guaranteed with a specific mouse RF coil, an effective ECG-gating system, and a BB-MRI sequence.