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Abstract #1236

Contrast-Enhanced Whole Heart Coronary MRI with Bolus Infusion of Gadobenate Dimeglumine at 1.5T

Peng Hu1, Jonathan Chan, Jouke Smink2, Beth Goddu, Kraig V. Kissinger, Lois A. Goepfert, Thomas H. Hauser, Neil M. Rofsky3, Warren J. Manning, Reza Nezafat

1Beth Israel Deaconess Medical Center, Boston, MA, United States; 2Philips Healthcare; 3Radiology, Beth Israel Deaconess Medical Center

We sought to investigate the contrast injection timing and rate for contrast-enhanced coronary artery MRI and compared the images acquired with optimized contrast timing to non-contrast T2-prep whole-heart SSFP coronary MRI at 1.5T. We studied time-resolved blood T1 after gadobenate dimeglumine (Gd-BOPTA) injection using three infusion schemes (bolus, slow infusion and hybrid). Subsequently, we evaluated an isotropic contrast-enhanced whole-heart coronary MRI method at 1.5T using an inversion-recovery SSFP sequence acquired after a bolus infusion of Gd-BOPTA. The contrast-enhanced coronary MRI increased blood SNR by 36% and increased coronary-myocardium CNR by 101%. There was no significant difference in image quality.