Contrast-Enhanced Whole Heart Coronary MRI with Bolus Infusion of Gadobenate Dimeglumine at 1.5T

Peng Hu¹, Jonathan Chan, Jouke Smink², Beth Goddu, Kraig V. Kissinger, Lois A. Goepfert, Thomas H. Hauser, Neil M. Rofsky³, Warren J. Manning, Reza Nezafat

We sought to investigate the contrast injection timing and rate for contrast-enhanced coronary artery MRI and compared the images acquired with optimized contrast timing to non-contrast T2-prep whole-heart SSFP coronary MRI at 1.5T. We studied time-resolved blood T1 after gadobenate dimeglumine (Gd-BOPTA) injection using three infusion schemes (bolus, slow infusion and hybrid). Subsequently, we evaluated an isotropic contrast-enhanced whole-heart coronary MRI method at 1.5T using an inversion-recovery SSFP sequence acquired after a bolus infusion of Gd-BOPTA. The contrast-enhanced coronary MRI increased blood SNR by 36% and increased coronary-myocardium CNR by 101%. There was no significant difference in image quality.