Yanfeng Meng1,2, Feng Zhang1,
Huidong Gu1, Jinnan Wang3, Chun Yuan1,
Zhaoqi Zhang2, Bensheng Qiu1, Xiaoming Yang1
1Radiology, University of Washington,
Seattle, WA, United States; 2Radiology, Beijing Anzhen Hospital,
Beijing, China; 3Clinical Sites Research Program, Philips Research
North America, Briarcliff Manor, NY, United States
This
study was to validate the feasibility of generating intravascular 3T MRI of
deep-seated arteries of near-human-sized swine by using a 3T-MR compatible
MR-imaging guidewire (MRIG). For in vitro testing, we compared SNRs generated
by a 0.032-inch MRIG and surface coils. For in vivo validation, we performed
intravenous MRI of the parallel-run iliofemoral arteries with this MRIG. The
SNR by the MRIG was higher than surface coils, and the iliofemoral arterial
walls were clearly delineated with the MRIG at a higher SNR than surface
coils. This study establishes the groundwork for further intravascular 3T MRI
of deep-seated arteries in humans.