Kerstin Ulrike Bauner1, Andreas Biffar2,
Daniel Theisen1, Torleif Sandner1, Andreas Greiser3,
Maximilian F. Reiser1, Bernd Wintersperger1
1Department of Clinical Radiology, LMU
Munich - Campus Grosshadern, Munich, Germany; 2Josef Lissner
Laboratory for Biomedical Imaging, LMU Munich - Campus Grosshadern, Munich; 3Siemens
medical solutions
At
a given field strength tissues present with specific T1-values. We
hypothesize, that infarcted myocardial tissue can be delineated from normal myocardium
by means of T1-maps in unenhanced and contrast-enhanced (Gadobutrol) scans.
Analysis of T1-values was performed for normal myocardium (MYO), infarcted
myocardium (CMI) and the left ventricular cavity (LVC). In addition T1-ratios
of MYO/LVC and CMI/LVC were calculated. T1-values of MYO and CMI and the
calculated ratios of MYO/LVC and CMI/LVC were significantly differenent in
pre-contrast and post-contrast scans. MR-measurements of T1-values with the
LVC as a reference allow for a differentiation of infarcted areas from normal
myocardial tissue.
Keywords