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Abstract #1307

On the Mechanism of Myocardial Edema Contrast in SSFP Imaging

Xiangzhi Zhou1, Veronica Rundell1, Ying Liu1, Richard Tang1, Rachel Klein1, Shivraman Giri2, Saurabh Shah3, Sven Zuehlsdorff3, Orlando Simonetti2, Debiao Li1, Rohan Dharmakumar1

1Northwestern University, Chicago, IL, United States; 2Ohio State University, Columbus, OH, United States; 3Siemens Medical Solutions USA, Inc., Chicago, IL, United States

The mechanism of bSSFP edema contrast in acute myocardial infarction imaging is not well understood. To assess the various mechanisms that enable the detection of myocardial edema on the basis on bSSFP imaging, controlled experiments were conducted in canine models subjected to ischemia reperfusion injury. Results show that relaxation and M0 changes have significant contribution to the detection of edematous myocardial zones following acute injury to the myocardium on the basis bSSFP imaging.