Myocardial BOLD Imaging Using Flow Compensated 2D Cine BSSFP

Xiangzhi Zhou¹, Sotirios A. Tsaftaris¹, Ying Liu¹, Richard Tang¹, Rachel Klein¹, Sven Zuehlsdorff², Debiao Li¹, Rohan Dharmakumar¹

Robust image quality is critical for reliable detection and evaluation of myocardial oxygenation changes with bSSFP BOLD imaging. This work evaluates the utility of 2D first-order motion compensation scheme to minimize flow/motion artifacts in cardiac phase-resolved bSSFP BOLD imaging using canines. Results show that compared to non-flow compensated bSSFP BOLD method, the proposed approach permits the evaluation of BOLD changes originating from coronary stenosis throughout the cardiac cycle.