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Abstract #1348

Contribution of the Blood Flow Evaluation by MRI in the Ascending Thoracic Aorta in Patients at Risk

Alain Lalande1,2, Clotilde Billard-Philip2, Marie Xavier1, Olivier Bouchot1,2, Eric Steinmetz2, Alexandre Cochet1, Paul Michael Walker1,2, Jean-Eric Wolf1,2, Franois Brunotte1,2

1LE2I, University of Burgundy, Dijon, France; 2University Hospital of Dijon, Dijon, France

Currently the evaluation of risk of rupture or dissection of the thoracic aorta is based on the aortic diameter, which is not a relevant parameter. To evaluate functional properties of the aorta, maximum blood flow velocity was evaluated in patients with well-classified diseases. 3D velocity imaging, acquired with velocity-encoded cine-MRI, and analysed with automatic post-processing allows the study of aortic blood flow. Compared with healthy subjects, the maximum blood flow velocity was higher for patients with bicuspid valve and lower for patients with the MYH11 mutation. There was no significant difference in patients with Marfan syndrome or annulo-aortic ectasia.