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Abstract #1356

Evaluation of the Coherence of Local Indices of Aortic Stiffness Calculated from Magnetic Resonance Data Using a Theoretical Model Derived from the Moens-Korteweg Equation

Anas Dogui1, Nadjia Kachenoura2, Alain De Cesare2, Muriel Lefort1, Mourad Bensalah1,3, Alain Herment1, Boutouyrie Pierre4,5, Elie Mousseaux1,6

1INSERM U678 ,UPMC, Paris, France; 2INSERM U678,UPMC, Paris, France; 3Radiology department, APHP, European Hospital Georges Pompidou,, Paris, France; 4INSERM U970, Paris, France; 5Pharmacology department, APHP, European Hospital Georges Pompidou, Paris, France; 6Radiology department, APHP, European Hospital Georges Pompidou, Paris, France

Aortic stiffness indices such as the local aortic deformability (AD) and the regional aortic pulse wave velocity (PWV) were assessed directly and non-invasively from morphological and hemodynamic magnetic resonance data on 40 subjects. The consistency of these indices was well described by a theoretical model derived from the Moens-Korteweg equation. A global aortic deformability (ADe) was estimated from PWV and carotid pulse pressure using the theoretical model and gave a similar description of stiffness of the ascending aorta as the local AD.