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Abstract #1370

Validation of Distensibility Measurements from MRI-Based Pulse Wave Velocity

Gabriel Acevedo-Bolton1, James Leung1, Chris Hardy2, Craig DeVincent, David Saloner1,3, Alison Meadows

1Radiology, UCSF, San Francisco, CA, United States; 2GE Global Research, Niskayuna, NY, United States; 3Radiology, VA Medical Center, San Francisco, CA

A one-dimensional Fourier Velocity Encoded MRI method was used to measure the Pulse Wave Velocity in a series of elastic tubes with differing elasticity. The distensibility of these tubes was also measured using mechanical testing. Good correlation was found between the distensibility measured by mechanical testing methods compared to that estimated from the MR velocimetry technique. This study provides confidence that MRV is a useful technique for determining the Pulse Wave Velocity in compliant vessels and could be used for assessing differing stages of vascular disease.