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Abstract #1440

Non-Contrast Time-Resolved MR Angiography Combining Multiple IR and N-1 Subtraction Arterial Spin Labeling Technique

Tokunori Kimura1, Shinichi Kitane2, Kazuhiro Sueoka3

1MRI Systems Development Department, Toshiba Medical Systems , Otawara, Tochigi, Japan; 2MRI Systems Development Department, Toshiba Medical Enginieering, Otawara, Tochigi, Japan; 3MRI Systems Development Department, Toshiba Medical Enginieering, Otawara, Tochigi, Japan


In-flow time-resolved MR angiography technique employing non-subtraction arterial spin labeling with multiple IR (mIR) technique was proposed. It was, however, difficult for mIR to suppress background tissue of wide range of T1 values from fat to CSF. We proposed alternative N-1 subtraction technique further to suppress background tissue signals while minimizing extra acquisition time. Volunteer brain study was performed on 1.5T imager with 2 mIR pulses designed to suppress brain tissues. Resulting background signals of fat and brain parenchyma were well suppressed only by adding extra acquisition time of 16 sec for base image then subtraction.