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Abstract #1487

Selection and Verification of a Throughput-Optimized Receive Array for Multiple-Mouse DCE-MRI

Marc Stephen Ramirez1, James Andrew Bankson1

1Department of Imaging Physics, The University of Texas M. D. Anderson Cancer Center, Houston, TX, United States

A variety of receive array coil configurations were simulated to determine acceptable parallel imaging reduction factors for use in accelerated multiple-mouse MRI. Based on these results, timing of accelerated multi-mouse DCE-MRI protocols were predicted and compared with timing of a single-mouse, single-coil DCE-MRI protocol to estimate improvements in throughput. The coil configuration that yielded the highest multi-mouse throughput improvement was determined. A phased-array coil based on the optimal configuration was designed, fabricated, and used for phantom imaging to verify that the predicted reduction factor per animal maintained image quality suitable for routine small-animal imaging studies.