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Abstract #1592

Supertoroid-Based Fusion of Cardiac Dt-Mri with Molecular and Physiological Information

Choukri Mekkaoui1,2, Marcel Jackowski3, Roberto Martuzzi1, Albert Sinusas1

1Yale University School of Medicine, New Haven, CT, United States; 2Harvard Medical School, Boston, MA, United States; 3University of So Paulo

The supertoroid-based representation enhances the three-dimensional perception of biological tissue structure and organization using DT-MRI. The presence of two additional free parameters in the supertoroidal function allows the tuning of the glyph surface in order to highlight different structural properties. Alternatively, these parameters can be used to fuse the visualization of structure with complimentary information provided by other modalities. In this work, we combined DT-MRI, MMP-targeted 99mTc-labeled radiotracer (RP805) uptake, and 201Tl perfusion on a porcine heart at 2-weeks post-MI, showing that the supertoroidal model can fuse information arising from different modalities into a unique and comprehensive visualization scheme.