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Abstract #1594

Validation of a Thalamus Segmentation Based on Local Difusion Information

Sarah Charlotte Mang1,2, Ania Busza, 2,3, Susanne Reiterer2, Wolfgang Grodd2, Uwe Klose2

1SIDT, German Cancer Research Center, Heidelberg, Germany; 2Section Experimental MR, Dept. of Neuroradiology, University Hospital Tuebingen, Tuebingen, Germany; 3MD/PhD Program, University of Massachusetts Medical School, Worcester, MA, United States

Fast and accurate segmentation of thalamic nuclei is important for clinical applications. We validated a segmentation method that is based on the classification of the local diffusion direction. We could show the correspondence between our segmentation results and anatomy known from a stereotactic atlas by Morel et al. in a group study of 63 healthy subjects. To show the similarity of individual subject results we compared the center-of-mass coordinates of the individual clusters and could show that they correspond well to each other.