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Abstract #1598

Novel Whole Brain DTI Segmentation and Diffusion Colour Mapping Technique for Tumour Diagnosis and Boundary Delineation

Timothy Lloyd Jones1, Ai Wern Chung2, B Anthony Bell1, Thomas Richard Barrick2

1Academic Neurosurgery Unit, St George's University of London, London, United Kingdom; 2Centre for Clinical Neurosciences, St George's University of London, London, United Kingdom

Accurate delineation of brain tumour boundaries is crucial for diagnosis, surveillance and treatment planning (e.g. image guided cyto-reductive surgery or radiotherapy). We propose a novel whole brain k-medians diffusion tensor imaging (DTI) algorithm generating Diffusion Colour Maps (DCMs) incorporating T2 relaxation, isotropic (p) and anisotropic (q) characteristics. In this study, we have applied our technique to a variety of intracranial pathology revealing characteristic colour patterns for each lesion type and clearly delineated tumour boundaries, suggesting a potential role in diagnosis and treatment planning.