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Abstract #1622

Parallel Line Scan Diffusion Tensor Imaging

Renxin Chu1, Bruno Madore1, Lawrence P. Panych1, Stephan E. Marier1

1Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States

Diffusion tensor imaging (DTI) has been widely used in the study of white matter-related diseases. Single-shot echo-planar imaging (EPI) is usually the preferred technique, but EPI images may exhibit severe geometric distortions, especially near the skull base. Line scan diffusion imaging (LSDI) is a one-dimensional Fourier encoding technique with considerable robustness against motion and geometric distortions. We present a parallel LSDI diffusion tensor imaging technique with acceleration along two dimensions, with 3D whole brain coverage and four-fold acceleration. The speed-up remarkably comes at no cost in SNR, and preserves the LSDI immunity to susceptibility-induced signal losses and geometric image distortions.