Characterization of White Matter Fasciculi with T1 Quantification: A Feasibility Study at High Field

Nico Dario Papinutto¹, Jorge Jovicich¹

Diffusion tensor imaging (DTI) of in-vivo human brains is a technique that is becoming widely used to get insight into normal and abnormal white matter anatomical connectivity. Characterization of pathologies with fractional anisotropy (FA) losses have been done, both at voxel level and along tracts. A promising method to further improve the characterization of main streamlines consists on adding relaxation times measurements. We present a simple method for T1 quantification of white matter tracts using sequences available in most commercial scanners.