Abstract #1683

Visualization of Intrarenal Water Transport by Diffusion Tensor Tractography

Michael Pedersen¹, Anders B. Ldrup¹, Kristian Karstoft¹, Eva A. Nielsen², Mette K. Hagensen², Peter A. Nielsen², Andreas Stavropoulos³, Bente Jespersen⁴, Steffen Ringgaard¹, Morten Smerup²

¹MR Research Center, Aarhus University Hosptial, Aarhus, Denmark; ²Institute of Clinical Medicine, Aarhus University Hosptial, Aarhus, Denmark; ³Dept. of Periodontology, Aarhus University, Aarhus, Denmark; ⁴Department of Nephrology, Aarhus University Hospital, Aarhus, Denmark

The aim of this study is to investigate if DTI can be used for imaging the principal route of free water in the kidney, and we hypothesize that this route can act as an indirect representation of the segments of nephrons going centripetally from the renal parenchyma to the collecting ducts. The orientation of medullary diffusion anisotrophy was visualized using a proposed DTI tractography method